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Sepsis Erodes CD8(+) Memory T Cell Protective Immunity Against an EBV Homolog in a 2B4-Dependent Manner

Epstein–Barr virus (EBV) reactivation commonly occurs following sepsis but the mechanisms underlying this are unknown. We utilized a murine EBV homolog (gHV) and the cecal ligation and puncture model of polymicrobial sepsis to study the impact of sepsis on gHV reactivation and CD8(+) T cell immune s...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Main Authors: Xie, J, Crepeau, RL, Chen, CW, Zhang, W, Otani, S, Coopersmith, CM, Ford, ML
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094871/
https://ncbi.nlm.nih.gov/pubmed/30624806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0718-292R
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