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Geldanamycin, a ligand of heat shock protein 90, inhibits herpes simplex virus type 2 replication both in vitro and in vivo

Previously, we discovered geldanamycin, a ligand of heat shock protein 90, effectively inhibited herpes simplex virus type 1 replication in vitro and in vivo (mouse encephalitis model). In this study, we demonstrate that geldanamycin has very strong activities against herpes simplex virus type 2 in...

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Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Li, Yu-Huan, Lu, Qiao-Ni, Wang, Hui-Qiang, Tao, Pei-Zhen, Jiang, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094714/
https://ncbi.nlm.nih.gov/pubmed/22909975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2012.67
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