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Calmodulin interacts with angiotensin‐converting enzyme‐2 (ACE2) and inhibits shedding of its ectodomain

Angiotensin‐converting enzyme‐2 (ACE2) is a regulatory protein of the renin–angiotensin system (RAS) and a receptor for the causative agent of severe‐acute respiratory syndrome (SARS), the SARS‐coronavirus. We have previously shown that ACE2 can be shed from the cell surface in response to phorbol e...

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Publicat a:FEBS Lett
Autors principals: Lambert, Daniel W., Clarke, Nicola E., Hooper, Nigel M., Turner, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094239/
https://ncbi.nlm.nih.gov/pubmed/18070603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.085
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