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Calmodulin interacts with angiotensin‐converting enzyme‐2 (ACE2) and inhibits shedding of its ectodomain

Angiotensin‐converting enzyme‐2 (ACE2) is a regulatory protein of the renin–angiotensin system (RAS) and a receptor for the causative agent of severe‐acute respiratory syndrome (SARS), the SARS‐coronavirus. We have previously shown that ACE2 can be shed from the cell surface in response to phorbol e...

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發表在:FEBS Lett
Main Authors: Lambert, Daniel W., Clarke, Nicola E., Hooper, Nigel M., Turner, Anthony J.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094239/
https://ncbi.nlm.nih.gov/pubmed/18070603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.085
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