Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL

Blastoid and pleomorphic mantle cell lymphomas (MCLs) are variants of aggressive histology MCL (AH-MCL). AH-MCL can arise de novo (AH-DN) or transform from prior classic variant MCL (AH-t). This study is the first integrated analysis of clinical and genomic characteristics of AH-MCL. Patient charact...

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Pubblicato in:Blood Adv
Autori principali: Jain, Preetesh, Zhang, Shaojun, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Nomie, Krystle, Gonzalez, Graciela Nogueras, Gonzalez-Pagan, Omarya, Hill, Holly A., Lee, Hun Ju, Fayad, Luis, Westin, Jason, Nastoupil, Loretta, Hagemeister, Frederick, Chen, Wendy, Oriabure, Onyeka, Badillo, Maria, Jiang, Changying, Yixin, Yao, Li, Shaoying, Tang, Guilin, Yin, C. Cameron, Patel, Keyur P., Medeiros, Leonard Jeffrey, Nair, Ranjit, Ahmed, Sairah, Iyer, Swaminathan P., Thirumurthi, Selvi, Champlin, Richard, Xu, Guofan, Tinsu, Pan, Santos, David, Wang, Ruiping, Han, Guangchun, Zhang, Jianhua, Song, Xingzhi, Neelapu, Sattva, Romaguera, Jorge, Futreal, Andy, Flowers, Christopher, Fowler, Nathan, Wang, Linghua, Wang, Michael L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094021/
https://ncbi.nlm.nih.gov/pubmed/32191807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001396
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