The prognostic impact of FLT3-ITD and NPM1 mutation in adult AML is age-dependent in the population-based setting

In acute myeloid leukemia (AML) FLT3 internal tandem duplication (ITD) and nucleophosmin 1 (NPM1) mutations provide prognostic information with clinical relevance through choice of treatment, but the effect of age and sex on these molecular markers has not been evaluated. The Swedish AML Registry co...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Juliusson, Gunnar, Jädersten, Martin, Deneberg, Stefan, Lehmann, Sören, Möllgård, Lars, Wennström, Lovisa, Antunovic, Petar, Cammenga, Jörg, Lorenz, Fryderyk, Ölander, Emma, Lazarevic, Vladimir Lj, Höglund, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094014/
https://ncbi.nlm.nih.gov/pubmed/32203582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001335
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