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Rank orders of mammalian pathogenicity-related PB2 mutations of avian influenza A viruses

The PB2 gene is one of the key determinants for the mammalian adaptation of avian influenza A viruses (IAVs). Although mammalian pathogenicity-related mutations (MPMs) in PB2 genes were identified in different genetic backgrounds of avian IAVs, the relative effects of single or multiple mutations on...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Lee, Chung-Young, An, Se-Hee, Choi, Jun-Gu, Lee, Youn-Jeong, Kim, Jae-Hong, Kwon, Hyuk-Joon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093554/
https://ncbi.nlm.nih.gov/pubmed/32210274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62036-5
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