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Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene
The polymerase of avian influenza A virus (AIV) is a heterotrimer composed of PB2, PB1, and PA. PB2 plays a role in overcoming the host barrier; however, the genetic prerequisites for avian PB2 to acquire mammalian pathogenic mutations have not been well elucidated. Previously, we identified a proto...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579056/ https://ncbi.nlm.nih.gov/pubmed/28860593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09560-z |
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