CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes

CYP2J2, a member of the Cytochrome P450 family of enzymes, is the most abundant epoxygenase in the heart and has multifunctional properties including bioactivation of arachidonic acid to epoxyeicosatrienoic acids, which, in turn, have been implicated in mediating several cardiovascular conditions. U...

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Published in:Sci Rep
Main Authors: Evangelista, Eric A., Aliwarga, Theresa, Sotoodehnia, Nona, Jensen, Paul N., McKnight, Barbara, Lemaitre, Rozenn N., Totah, Rheem A., Gharib, Sina A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093536/
https://ncbi.nlm.nih.gov/pubmed/32210298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62174-w
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