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A sensitive and improved throughput UPLC-MS/MS quantitation method of total cytochrome P450 mediated arachidonic acid metabolites that can separate regio-isomers and cis/trans-EETs from human plasma
A method for the detection and quantification of hydroxyl and epoxy arachidonic acid (AA(1)) metabolites in human plasma was developed using liquid-liquid extraction, phospholipid saponification followed by derivatization of the acid moiety and liquid chromatographic tandem mass spectrometric detect...
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| Publicado no: | Chem Phys Lipids |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269592/ https://ncbi.nlm.nih.gov/pubmed/30201384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2018.09.004 |
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