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SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity

Sirtuin 3 (SIRT3) is a type III histone deacetylase that inhibits cardiac hypertrophy. It is mainly localized in the mitochondria and is thus implicated in mitochondrial metabolism. Recent studies have shown that SIRT3 can also accumulate in the nuclear under stressed conditions, and participated in...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Feng, Xiaojun, Wang, Yanan, Chen, Wenxu, Xu, Suowen, Li, Lingli, Geng, Yadi, Shen, Aizong, Gao, Hui, Zhang, Lei, Liu, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093179/
https://ncbi.nlm.nih.gov/pubmed/32139662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102862
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