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SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity
Sirtuin 3 (SIRT3) is a type III histone deacetylase that inhibits cardiac hypertrophy. It is mainly localized in the mitochondria and is thus implicated in mitochondrial metabolism. Recent studies have shown that SIRT3 can also accumulate in the nuclear under stressed conditions, and participated in...
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| Pubblicato in: | Aging (Albany NY) |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7093179/ https://ncbi.nlm.nih.gov/pubmed/32139662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102862 |
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