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Broadly Protective Multivalent OspA Vaccine against Lyme Borreliosis, Developed Based on Surface Shaping of the C-Terminal Fragment

The development of vaccines for prevention of diseases caused by pathogenic species can encounter major obstacles if high sequence diversity is observed between individual strains. Therefore, development might be restricted either to conserved antigens, which are often rare, or to multivalent vaccin...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Nayak, Abhijeet, Schüler, Wolfgang, Seidel, Stefan, Gomez, Ivan, Meinke, Andreas, Comstedt, Pär, Lundberg, Urban
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093141/
https://ncbi.nlm.nih.gov/pubmed/31932330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00917-19
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