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Broadly Protective Multivalent OspA Vaccine against Lyme Borreliosis, Developed Based on Surface Shaping of the C-Terminal Fragment

The development of vaccines for prevention of diseases caused by pathogenic species can encounter major obstacles if high sequence diversity is observed between individual strains. Therefore, development might be restricted either to conserved antigens, which are often rare, or to multivalent vaccin...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Nayak, Abhijeet, Schüler, Wolfgang, Seidel, Stefan, Gomez, Ivan, Meinke, Andreas, Comstedt, Pär, Lundberg, Urban
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093141/
https://ncbi.nlm.nih.gov/pubmed/31932330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00917-19
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