Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination

Germinal centres (GCs) are T follicular helper cell (Tfh)-dependent structures that form in response to vaccination, producing long-lived antibody secreting plasma cells and memory B cells that protect against subsequent infection. With advancing age the GC and Tfh cell response declines, resulting...

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Veröffentlicht in:eLife
Hauptverfasser: Stebegg, Marisa, Bignon, Alexandre, Hill, Danika Lea, Silva-Cayetano, Alyssa, Krueger, Christel, Vanderleyden, Ine, Innocentin, Silvia, Boon, Louis, Wang, Jiong, Zand, Martin S, Dooley, James, Clark, Jonathan, Liston, Adrian, Carr, Edward, Linterman, Michelle A
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Immunology and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093110/
https://ncbi.nlm.nih.gov/pubmed/32204792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52473
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