Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model

Tumor associated fibroblasts (TAFs) are key stromal cells mediating the desmoplastic reaction and being partially responsible for the drug-resistance and immunosuppressive microenvironment formation in solid tumors. Delivery of genotoxic drugs off-targetedly to kill TAFs results in production of Wnt...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biomaterials
Auteurs principaux: Xu, Huan, Hu, Mengying, Liu, Mengrui, An, Sai, Guan, Kaiyun, Wang, Menglin, Li, Lei, Zhang, Jing, Li, Jun, Huang, Leaf
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093100/
https://ncbi.nlm.nih.gov/pubmed/31986348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119769
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