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Structural Origin of the Large Redox-Linked Reorganization in the 2-Oxoglutarate Dependent Oxygenase, TauD
2-Oxoglutarate (2OG)-dependent oxygenases catalyze a wide range of chemical transformations via C─H bond activation. Prior studies raised the question of whether substrate hydroxylation by these enzymes occurs via a hydroxyl rebound or alkoxide mechanism and highlighted the need to understand the th...
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| Veröffentlicht in: | J Am Chem Soc |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7092798/ https://ncbi.nlm.nih.gov/pubmed/31475523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07493 |
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