Elav-Mediated Exon Skipping and Alternative Polyadenylation of the Dscam1 Gene Are Required for Axon Outgrowth

Many metazoan genes express alternative long 3′ UTR isoforms in the nervous system, but their functions remain largely unclear. In Drosophila melanogaster, the Dscam1 gene generates short and long (Dscam1-L) 3′ UTR isoforms because of alternative polyadenylation (APA). Here, we found that the RNA-bi...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Zhang, Zhiping, So, Kevin, Peterson, Ryan, Bauer, Matthew, Ng, Henry, Zhang, Yong, Kim, Jung Hwan, Kidd, Thomas, Miura, Pedro
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092717/
https://ncbi.nlm.nih.gov/pubmed/31242415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.083
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