Oligomannuronate prevents mitochondrial dysfunction induced by IAPP in RINm5F islet cells by inhibition of JNK activation and cell apoptosis

BACKGROUND: Oligomannuronates (OM) are natural products from alginate that is frequently used as food supplement. The aim of this study was to investigate the in vitro protective effects of OM on RINm5F cells against human Islet amyloid polypeptide (IAPP) induced mitochondrial dysfunction, as well a...

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Detalhes bibliográficos
Publicado no:Chin Med
Main Authors: Liu, Xi, Li, Qiong, Cheng, Xiaolei, Liu, Zhichun, Zhao, Xiaoliang, Zhang, Shuai, Yu, Guangli, Zhao, Xia, Hao, Jiejie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092590/
https://ncbi.nlm.nih.gov/pubmed/32226477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-020-00310-4
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