Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation

We previously reported that treatment with a JNK inhibitory peptide (11R-JNKI) prevents islet apoptosis and enhances the islet function in vivo. In the present study, we explored more efficient JNK inhibitors. The inhibition of the JNK activity by five types of deletion peptides in 11R-JNKI was inve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Noguchi, Hirofumi, Miyagi-Shiohira, Chika, Nakashima, Yoshiki, Ebi, Nana, Hamada, Eri, Tamaki, Yoshihito, Kuwae, Kazuho, Kobayashi, Naoya, Saitoh, Issei, Watanabe, Masami
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056537/
https://ncbi.nlm.nih.gov/pubmed/30038242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29481-9
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