Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation

We previously reported that treatment with a JNK inhibitory peptide (11R-JNKI) prevents islet apoptosis and enhances the islet function in vivo. In the present study, we explored more efficient JNK inhibitors. The inhibition of the JNK activity by five types of deletion peptides in 11R-JNKI was inve...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Noguchi, Hirofumi, Miyagi-Shiohira, Chika, Nakashima, Yoshiki, Ebi, Nana, Hamada, Eri, Tamaki, Yoshihito, Kuwae, Kazuho, Kobayashi, Naoya, Saitoh, Issei, Watanabe, Masami
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056537/
https://ncbi.nlm.nih.gov/pubmed/30038242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29481-9
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