Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein

In this report, we present a new benzoxazole derivative endowed with inhibitory activity against the HIV-1 nucleocapsid protein (NC). NC is a 55-residue basic protein with nucleic acid chaperone properties, which has emerged as a novel and potential pharmacological target against HIV-1. In the pursu...

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Detaylı Bibliyografya
Yayımlandı:Eur J Med Chem
Asıl Yazarlar: Gamba, Elia, Mori, Mattia, Kovalenko, Lesia, Giannini, Alessia, Sosic, Alice, Saladini, Francesco, Fabris, Dan, Mély, Yves, Gatto, Barbara, Botta, Maurizio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092364/
https://ncbi.nlm.nih.gov/pubmed/29324338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.12.073
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