T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates

Immune responses against multiple epitopes are required for the prevention of hepatitis C virus (HCV) infection, and the progression to phase I trials of candidates may be guided by comparative immunogenicity studies in non-human primates. Four vectors, DNA, SFV, human serotype 5 adenovirus (HuAd5)...

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Udgivet i:Gene Ther
Main Authors: Rollier, C S, Verschoor, E J, Verstrepen, B E, Drexhage, J A R, Paranhos-Baccala, G, Liljeström, P, Sutter, G, Arribillaga, L, Lasarte, J J, Bartosch, B, Cosset, F-L, Inchauspe, G, Heeney, J L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091906/
https://ncbi.nlm.nih.gov/pubmed/27416077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.55
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