HSCT may lower leukemia risk in ELANE neutropenia: a before–after study from the French Severe Congenital Neutropenia Registry

ELANE neutropenia is associated with myelodysplasia and acute leukemia (MDS–AL), and severe infections. Because the MDS–AL risk has also been shown to be associated with exposure to GCSF, since 2005, in France, patients receiving high daily GCSF doses (>15 μg/kg/day) are eligible for HSCT, in add...

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Détails bibliographiques
Publié dans:Bone Marrow Transplant
Auteurs principaux: Rotulo, Gioacchino Andrea, Beaupain, Blandine, Rialland, Fanny, Paillard, Catherine, Nachit, Ouahiba, Galambrun, Claire, Gandemer, Virginie, Bertrand, Yves, Neven, Benedicte, Dore, Eric, Moshous, Despina, Filhon, Bruno, Aladjdi, Nathalie, Sicre de Fontbrune, Flore, de la Tour, Regis Peffault, Ouachee, Marie, Bellanne-Chantelot, Christine, Dalle, Jean-Hugues, Donadieu, Jean
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091645/
https://ncbi.nlm.nih.gov/pubmed/31992846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41409-020-0800-1
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