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Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction

Vinculin is a universal adaptor protein that transiently reinforces the mechanical stability of adhesion complexes. It stabilizes mechanical connections that cells establish between the actomyosin cytoskeleton and the extracellular matrix via integrins or to neighboring cells via cadherins, yet litt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Kluger, Carleen, Braun, Lukas, Sedlak, Steffen M., Pippig, Diana A., Bauer, Magnus S., Miller, Ken, Milles, Lukas F., Gaub, Hermann E., Vogel, Viola
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091509/
https://ncbi.nlm.nih.gov/pubmed/32109366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.042
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