Protection of Mice Against Lethal Rabies Virus Challenge Using Short Interfering RNAs (siRNAs) Delivered Through Lentiviral Vector

The antiviral potential of small interfering RNAs (siRNAs) targeting rabies virus (RV) polymerase (L) and nucleoprotein (N) genes delivered through lentiviral vector was investigated. For in vitro evaluation, siRNAs expressing BHK-21 cell lines (BHK-L and BHK-N) were developed using transduction wit...

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Vydáno v:Mol Biotechnol
Hlavní autoři: Singh, Niraj K., Meshram, Chetan D., Sonwane, Arvind A., Dahiya, Shyam S., Pawar, Sachin S., Chaturvedi, V. K., Saini, Mohini, Singh, R. P., Gupta, Praveen K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090658/
https://ncbi.nlm.nih.gov/pubmed/23877894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-013-9685-1
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