Protection of Mice Against Lethal Rabies Virus Challenge Using Short Interfering RNAs (siRNAs) Delivered Through Lentiviral Vector

The antiviral potential of small interfering RNAs (siRNAs) targeting rabies virus (RV) polymerase (L) and nucleoprotein (N) genes delivered through lentiviral vector was investigated. For in vitro evaluation, siRNAs expressing BHK-21 cell lines (BHK-L and BHK-N) were developed using transduction wit...

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Bibliografiske detaljer
Udgivet i:Mol Biotechnol
Main Authors: Singh, Niraj K., Meshram, Chetan D., Sonwane, Arvind A., Dahiya, Shyam S., Pawar, Sachin S., Chaturvedi, V. K., Saini, Mohini, Singh, R. P., Gupta, Praveen K.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090658/
https://ncbi.nlm.nih.gov/pubmed/23877894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-013-9685-1
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