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Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous distribution of TFs in the nucleus impacts on gene expression. Thus, it...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Verneri, Paula, Vazquez Echegaray, Camila, Oses, Camila, Stortz, Martin, Guberman, Alejandra, Levi, Valeria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089971/
https://ncbi.nlm.nih.gov/pubmed/32251342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62235-0
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