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Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous distribution of TFs in the nucleus impacts on gene expression. Thus, it...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Verneri, Paula, Vazquez Echegaray, Camila, Oses, Camila, Stortz, Martin, Guberman, Alejandra, Levi, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089971/
https://ncbi.nlm.nih.gov/pubmed/32251342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62235-0
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