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Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous distribution of TFs in the nucleus impacts on gene expression. Thus, it...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Verneri, Paula, Vazquez Echegaray, Camila, Oses, Camila, Stortz, Martin, Guberman, Alejandra, Levi, Valeria
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089971/
https://ncbi.nlm.nih.gov/pubmed/32251342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62235-0
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