Decreased Efficacy of Doxorubicin Corresponds With Modifications in Lipid Metabolism Markers and Fatty Acid Profiles in Breast Tumors From Obese vs. Lean Mice

Breast cancer cells modulate lipid and fatty acid metabolism to sustain proliferation. The role of adipocytes in cancer treatment efficacy remains, however, to be fully elucidated. We investigated whether diet-induced obesity (DIO) affects the efficacy of doxorubicin treatment in a breast tumor-bear...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Mentoor, Ilze, Nell, Theo, Emjedi, Zaakiyah, van Jaarsveld, Paul J., de Jager, Louis, Engelbrecht, Anna-Mart
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089940/
https://ncbi.nlm.nih.gov/pubmed/32257945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00306
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