Use of Pharmacogenetic Data to Guide Individualized Opioid Prescribing After Surgery

BACKGROUND. In spite of the current strategies aimed at avoiding opioid over prescription by implementing institutional guidelines, the use of opioids after surgical procedures remains highly variable. It is well known that opioids are activated by the cytochrome p450 CYP2D6 enzyme in order to exert...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Surgery
Hauptverfasser: Rocco, Raffaele, Thiels, Cornelius A., Ubl, Daniel S., Moyer, Ann M., Habermann, Elizabeth B., Cassivi, Stephen D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089776/
https://ncbi.nlm.nih.gov/pubmed/31320226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.04.033
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