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Use of Pharmacogenetic Data to Guide Individualized Opioid Prescribing After Surgery

BACKGROUND. In spite of the current strategies aimed at avoiding opioid over prescription by implementing institutional guidelines, the use of opioids after surgical procedures remains highly variable. It is well known that opioids are activated by the cytochrome p450 CYP2D6 enzyme in order to exert...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Rocco, Raffaele, Thiels, Cornelius A., Ubl, Daniel S., Moyer, Ann M., Habermann, Elizabeth B., Cassivi, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089776/
https://ncbi.nlm.nih.gov/pubmed/31320226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.04.033
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