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Clearing debris
A new small molecule that targets the vacuolar H(+)-ATPase activates autophagy, inhibits mTORC1 signaling, and displays potential for clearing toxic protein aggregates involved in neurodegenerative diseases.
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| Udgivet i: | Nat Chem Biol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7089575/ https://ncbi.nlm.nih.gov/pubmed/31285594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0320-8 |
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