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N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder

Individuals with chronic kidney disease have elevated levels of oxidative stress and are at a significantly higher risk of skeletal fracture. Advanced glycation end products (AGEs), which accumulate in bone and compromise mechanical properties, are known to be driven in part by oxidative stress. The...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Allen, Matthew R., Wallace, Joseph, McNerney, Erin, Nyman, Jeffry, Avin, Keith, Chen, Neal, Moe, Sharon
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089527/
https://ncbi.nlm.nih.gov/pubmed/32203558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230379
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