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N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder

Individuals with chronic kidney disease have elevated levels of oxidative stress and are at a significantly higher risk of skeletal fracture. Advanced glycation end products (AGEs), which accumulate in bone and compromise mechanical properties, are known to be driven in part by oxidative stress. The...

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Publicado en:PLoS One
Main Authors: Allen, Matthew R., Wallace, Joseph, McNerney, Erin, Nyman, Jeffry, Avin, Keith, Chen, Neal, Moe, Sharon
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089527/
https://ncbi.nlm.nih.gov/pubmed/32203558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230379
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