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Design, synthesis and activity evaluation of mannose-based DC-SIGN antagonists
In this article, we describe the design, synthesis and activity evaluation of glycomimetic DC-SIGN antagonists, that use a mannose residue to anchor to the protein carbohydrate recognition domain (CRD). The molecules were designed from the structure of the known pseudo-mannobioside antagonist 1, by...
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| Publicado no: | Mol Divers |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7089406/ https://ncbi.nlm.nih.gov/pubmed/21076980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11030-010-9285-y |
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