NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo

Flaviviruses such as yellow fever, dengue or Zika viruses are responsible for significant human and veterinary diseases worldwide. These viruses contain an RNA genome, prone to mutations, which enhances their potential to emerge as pathogens. Bamaga virus (BgV) is a mosquito-borne flavivirus in the...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Colmant, Agathe M. G., Bielefeldt-Ohmann, Helle, Vet, Laura J., O’Brien, Caitlin A., Bowen, Richard A., Hartwig, Airn E., Davis, Steven, Piyasena, Thisun B. H., Habarugira, Gervais, Harrison, Jessica J., Hobson-Peters, Jody, Hall, Roy A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089401/
https://ncbi.nlm.nih.gov/pubmed/32203536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008166
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