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NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo

Flaviviruses such as yellow fever, dengue or Zika viruses are responsible for significant human and veterinary diseases worldwide. These viruses contain an RNA genome, prone to mutations, which enhances their potential to emerge as pathogens. Bamaga virus (BgV) is a mosquito-borne flavivirus in the...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Colmant, Agathe M. G., Bielefeldt-Ohmann, Helle, Vet, Laura J., O’Brien, Caitlin A., Bowen, Richard A., Hartwig, Airn E., Davis, Steven, Piyasena, Thisun B. H., Habarugira, Gervais, Harrison, Jessica J., Hobson-Peters, Jody, Hall, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089401/
https://ncbi.nlm.nih.gov/pubmed/32203536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008166
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