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Studying Human Pathogens in Animal Models: Fine Tuning the Humanized Mouse

Humanized mice are crucial tools for studying human pathogens in systemic situations. An animal model of human coronavirus infectious disease has been generated by gene transfer of the human receptor for virus-cell interaction (aminopeptidase N, APN, CD13) into mice. We showed that in vitro and in v...

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Dettagli Bibliografici
Pubblicato in:Transgenic Res
Autori principali: Lassnig, Caroline, Kolb, Andreas, Strobl, Birgit, Enjuanes, Luis, Müller, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Kluwer Academic Publishers 2005
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088949/
https://ncbi.nlm.nih.gov/pubmed/16315087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-005-1676-y
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