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Development of a transgenic mouse model susceptible to human coronavirus 229E

Human coronavirus (HCoV) 229E is a group 1 coronavirus and is specific to humans. So far, no animal model is available to study the pathogenesis of infection by HCoV-229E. We show here that the expression of aminopeptidase N (APN, also termed CD13), the receptor for HCoV-229E, is required but not su...

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Detalhes bibliográficos
Main Authors: Lassnig, Caroline, Sanchez, Carlos M., Egerbacher, Monika, Walter, Ingrid, Majer, Susanne, Kolbe, Thomas, Pallares, Pilar, Enjuanes, Luis, Müller, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140478/
https://ncbi.nlm.nih.gov/pubmed/15919828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408589102
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