Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin

[Image: see text] The pancreatic peptide hormone, amylin, plays a critical role in the control of appetite, and synergizes with other key metabolic hormones such as glucagon-like peptide 1 (GLP-1). There is opportunity to develop potent and long-acting analogues of amylin or hybrids between these an...

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Veröffentlicht in:ACS Pharmacol Transl Sci
Hauptverfasser: Bower, Rebekah L., Yule, Lauren, Rees, Tayla A., Deganutti, Giuseppe, Hendrikse, Erica R., Harris, Paul W. R., Kowalczyk, Renata, Ridgway, Zachary, Wong, Amy G., Swierkula, Katarzyna, Raleigh, Daniel P., Pioszak, Augen A., Brimble, Margaret A., Reynolds, Christopher A., Walker, Christopher S., Hay, Debbie L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088893/
https://ncbi.nlm.nih.gov/pubmed/32219203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00002
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