Preparation, characterization and preliminary in vivo studies of inactivated SARS-CoV vaccine

A large quantity of SARS-CoV virus was proliferated in Vero cells, inactivated with β-propiolactone, then purified by Sepharose 4FF column chromatography to prepare inactivated vaccine. The vaccine was identified by Western blot, mass spectrographic analysis, ELISA and electron microscopy. The vacci...

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Detalhes bibliográficos
Publicado no:Chin Sci Bull
Main Authors: Tang, Lin, Wang, Jian, Qin, Ede, Zhu, Qingyu, Yu, Man, Ding, Zhifen, Shi, Huiying, Cheng, Xiaojie, Wang, Caiping, Chang, Guohui, Li, Shuangli, Zhang, Xumin, Chen, Xishu, Yu, Jun, Chen, Ze
Formato: Artigo
Idioma:Inglês
Publicado em: Science in China Press 2003
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088751/
https://ncbi.nlm.nih.gov/pubmed/32214708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1360/03wc464
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