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The past, present, and future of costimulation blockade in organ transplantation

PURPOSE OF REVIEW: Manipulating costimulatory signals has been shown to alter T cell responses and prolong graft survival in solid organ transplantation. Our understanding of and ability to target various costimulation pathways continues to evolve. RECENT FINDINGS: Since the approval of belatacept i...

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Detalhes bibliográficos
Publicado no:Curr Opin Organ Transplant
Main Authors: Schroder, Paul M., Fitch, Zachary W., Schmitz, Robin, Choi, Ashley Y., Kwun, Jean, Knechtle, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088447/
https://ncbi.nlm.nih.gov/pubmed/31157670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000656
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