Ultrasensitive genetically encoded indicator for hydrogen peroxide identifies roles for the oxidant in cell migration and mitochondrial function

Hydrogen peroxide (H(2)O(2)) is a key redox intermediate generated within cells. Existing probes for H(2)O(2) have not solved the problem of detection of the ultra-low concentrations of the oxidant: these reporters are either not sensitive enough, or pH-dependent, or insufficiently bright, or not fu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Pak, Valeriy V., Ezeriņa, Daria, Lyublinskaya, Olga G., Pedre, Brandán, Tyurin-Kuzmin, Pyotr A., Mishina, Natalie M., Thauvin, Marion, Young, David, Wahni, Khadija, Gache, Santiago Agustín Martínez, Demidovich, Alexandra D., Ermakova, Yulia G., Maslova, Yulia D., Shokhina, Arina G., Eroglu, Emrah, Bilan, Dmitry S., Bogeski, Ivan, Michel, Thomas, Vriz, Sophie, Messens, Joris, Belousov, Vsevolod V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088435/
https://ncbi.nlm.nih.gov/pubmed/32130885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.02.003
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