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On the different sources of cooperativity in pH titrating sites of a membrane protein channel
ABSTRACT. Cooperative interactions play a central role in the regulation of protein functions. Here we show that in multi-site systems like ion channels the application of the Hill formalism could require a combination of different experiments, even involving site-directed mutagenesis, to identify t...
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| Publicado no: | Eur Phys J E Soft Matter |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7087919/ https://ncbi.nlm.nih.gov/pubmed/26987733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1140/epje/i2016-16029-2 |
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