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Crystal Structure of Keratin 1/10(C401A) 2B Heterodimer Demonstrates a Proclivity for the C-Terminus of Helix 2B to Form Higher Order Molecular Contacts

We previously determined the crystal structure of the wild-type keratin 1/10 helix 2B heterodimer at 3.3 Å resolution. We proposed that the resolution of the diffraction data was limited due to the crystal packing effect from keratin 10 (K10) residue Cys401. Cys401(K10) formed a disulfide-linkage wi...

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Detalhes bibliográficos
Publicado no:Yale J Biol Med
Main Authors: Lomakin, Ivan B., Hinbest, Alexander J., Ho, Minh, Eldirany, Sherif A., Bunick, Christopher G.
Formato: Artigo
Idioma:Inglês
Publicado em: YJBM 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087056/
https://ncbi.nlm.nih.gov/pubmed/32226330
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