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Molecular Modeling of Pathogenic Mutations in the Keratin 1B Domain
Keratin intermediate filaments constitute the primary cytoskeletal component of epithelial cells. Numerous human disease phenotypes related to keratin mutation remain mechanistically elusive. Our recent crystal structures of the helix 1B heterotetramer from keratin 1/10 enabled further investigation...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555247/ https://ncbi.nlm.nih.gov/pubmed/32927888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186641 |
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