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Modulation of Coiled-Coil Binding Strength and Fusogenicity through Peptide Stapling

[Image: see text] Peptide stapling is a technique which has been widely employed to constrain the conformation of peptides. One of the effects of such a constraint can be to modulate the interaction of the peptide with a binding partner. Here, a cysteine bis-alkylation stapling technique was applied...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Crone, Niek S. A., Kros, Alexander, Boyle, Aimee L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086394/
https://ncbi.nlm.nih.gov/pubmed/32058706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00009
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