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Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion
[Image: see text] We have developed a model system for membrane fusion that utilizes lipidated derivatives of a heterodimeric coiled-coil pair dubbed E(3) (EIAALEK)(3) and K(3) (KIAALKE)(3). In this system, peptides are conjugated to a lipid anchor via a poly(ethylene glycol) (PEG) spacer, and this...
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| Veröffentlicht in: | Langmuir |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American
Chemical Society
2017
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666511/ https://ncbi.nlm.nih.gov/pubmed/28980816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.7b02931 |
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