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IL-37/ STAT3/ HIF-1α negative feedback signaling drives gemcitabine resistance in pancreatic cancer

Human interleukin (IL)-37 is a member of the IL-1 family with potent anti-inflammatory and immunosuppressive properties. Previously, it has been reported that IL-37 suppresses tumor growth and progression. However, the roles of IL-37 in pancreatic cancer development and chemo-resistance remain unkno...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Zhao, Tiansuo, Jin, Fanjie, Xiao, Di, Wang, Hongwei, Huang, Chongbiao, Wang, Xiuchao, Gao, Song, Liu, Jing, Yang, Shengyu, Hao, Jihui
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086367/
https://ncbi.nlm.nih.gov/pubmed/32226541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42416
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